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The mitochondrial inner membrane nicotinamide nucleotide transhydrogenase (NNT) also produces NADPH and this serves to couple reductive stress-induced H 2 O 2 production to NNT-associated NADPH and glutathione redox mechanisms [17]

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Mitochondrial Therapy Recently, there has been a growing interest in mitochondrial therapy, especially in the form of artificial mitochondrial transfer/transplant (AMT/T) or the use of mitochondria as a “Living Drug”